发明名称 FUSION PEPTIDE THERAPEUTIC COMPOSITIONS
摘要 PROBLEM TO BE SOLVED: To provide therapeutic compositions capable of improving the enhanced efficacy of a peptide active therapeutic agent to be achieved, in relation to the peptide active therapeutic agent alone.SOLUTION: Therapeutic compositions contain fusion proteins (FPs) including elastin-like peptides (ELPs) and peptide active therapeutic agents. Enhanced efficacy of the peptide active therapeutic agent in the therapeutic composition may include improved solubility, bioavailability, bio-unavailability, half-life, etc., as compared to corresponding compositions containing the same peptide active therapeutic agent without associated ELPs.
申请公布号 JP2014051510(A) 申请公布日期 2014.03.20
申请号 JP20130217181 申请日期 2013.10.18
申请人 PHASEBIO PHARMACEUTICALS INC 发明人 CHILKOTI ASHUTOSH
分类号 A61K38/00;A61K38/21;A61K38/22;A61K38/27;A61K38/28;A61K38/45;A61K38/46;A61K47/48;A61K48/00;C07K14/78;C07K19/00;C12N15/09 主分类号 A61K38/00
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