| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to molecular biology and can be used in diagnostic studies aimed at detecting acute intestinal infection (AII) agents. Disclosed is a set of differentiating oligonucleotides (probes), which enables to determine, in a biological sample, DNA of pathogenic microorganisms which cause AII, and specific identification thereof, where said microorganisms relate to a group which includes Shigella spp. and Enteroinvasive E.coli (EIEC), Salmonella spp., Campylobacter Jejuni, Proteus mirabilis, Klebsiella pneumoniae.EFFECT: described is design of a biochip on which is immobilised a set of probes disclosed herein, designed to perform rapid analysis of AII agents in clinical samples and material obtained from environmental media.2 cl, 4 tbl, 2 dwg, 5 ex |
