摘要 |
1,133,916. Ergocryptine. SOCIETAFARMACEUTICI ITALIA. 17 July, 1967 [22 July, 1966], No. 32828/67. Heading C2C. Ergocryptine is produced by cultivating the new microorganism Claviceps purpurea FI 101a in submerged culture under aerobic conditions in a liquid nutrient medium containing a source of carbon, nitrogen, and mineral salts at a temperature of 20‹ to 30‹ C. and a pH of between 4 and 6À5 for from 8 to 16 days. The liquid nutrient medium may contain, as a carbon source, glucose, saccharose, mannite, sorbite, glycerine, citric acid or succinic acid, as a nitrogen source ammonia, asparagine, peptone, casein hydrolysates and ammonium salts. Suitable mineral salts include chlorides, phosphates and sulphates of magnesium, iron, zinc, manganese, and potassium.
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