| 发明名称 |
LEWIS ACID MEDIATED SYNTHESIS OF CYCLIC ESTERS |
| 摘要 |
<p>Methods for the synthesis of cyclic phosphonic acid diesters from 1,3-diols are described, whereby cyclic phosphonic acid diesters are produced by reacting a chiral 1,3-diol and an activated phosphonic acid in the presence of a Lewis acid.</p> |
| 申请公布号 |
EP1753762(B1) |
申请公布日期 |
2014.03.19 |
| 申请号 |
EP20050758526 |
申请日期 |
2005.06.03 |
| 申请人 |
METABASIS THERAPEUTICS, INC. |
发明人 |
MARTIN, KEVIN |
| 分类号 |
C07D471/02;A61K31/675;C07F9/06;C07F9/28;C07F9/6512;C07F9/6571 |
主分类号 |
C07D471/02 |
| 代理机构 |
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| 地址 |
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