摘要 |
The present invention provides cyclo ACH-RGDK which is prepared by inserting aminocyclohexanecarboxylic acid (ACH) between lysine and aspartate of cyclo Arg-Gly-Asp-Lys (cyclo RGDK peptide) which is known for having selectivity to cancer cells by peptide bonds; novel PET contrast compounds in which cyclo ACH-RGDK is conjugated with radioisotope, 64Cu2+, through a ligand; an intermediate of the novel compounds; a method for preparing the same; and a PET contrast agent containing the novel compounds. |