This invention relates to methods for the detection of a bovine that is affected by or carrier of brachyspina. It is based on the identification of a 3.3 Kb deletion in the bovine FANCI gene that is shown to cause the brachyspina syndrome. The present invention provides methods and uses for determining whether a bovine is affected by or carrier of brachyspina by analyzing its genomic DNA or its RNA. The methods can be used to perform marker assisted selection or genomic selection for increased fertility in said bovine.
申请公布号
EP2707497(A1)
申请公布日期
2014.03.19
申请号
EP20110776127
申请日期
2011.09.22
申请人
UNIVERSITE DE LIEGE;UNIVERSITY OF COPENHAGEN
发明人
GEORGES, MICHEL;COPPIETERS, WOUTER;CHARLIER, CAROLE;AGERHOLM, JOERGEN STEEN;FREDHOLM, MERETE;KARLSKOV-MORTENSEN, PETER