| 发明名称 |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors |
| 摘要 |
In its many embodiments, the present invention provides a method of inhibiting one or more cyclin dependent kinases in a patient comprising administering to said patient a therapeutically effective amount of at least one pyrazolo[1,5-a]pyrimidine compound or a pharmaceutical composition comprising such compound, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions. An example pyrazolo[1,5-a]pyrimidine compound useful in the present invention is shown below: |
| 申请公布号 |
US8673924(B2) |
申请公布日期 |
2014.03.18 |
| 申请号 |
US20070788847 |
申请日期 |
2007.04.20 |
| 申请人 |
GUZI TIMOTHY J.;PARUCH KAMIL;DWYER MICHAEL P.;DOLL RONALD J.;GIRIJAVALLABHAN VIYYOOR M.;MALLAMS ALAN;ALVAREZ CARMEN S.;KEERTIKAR KARTIK M.;RIVERA JOCELYN;CHAN TIN-YAU;MADISON VINCENT S.;FISCHMANN THIERRY O.;DILLARD LAWRENCE W.;TRAN VINH D.;HE ZHENMIN;JAMES RAY ANTHONY;PARK HAENGSOON;PARADKAR VIDYADHAR M.;HOBBS DOUGLAS WALSH;KIRSCHMEIER PAUL;BANNERJI RAJAT;MERCK SHARP & DOHME CORP.;PHARMACOPEIA, LLC |
发明人 |
GUZI TIMOTHY J.;PARUCH KAMIL;DWYER MICHAEL P.;DOLL RONALD J.;GIRIJAVALLABHAN VIYYOOR M.;MALLAMS ALAN;ALVAREZ CARMEN S.;KEERTIKAR KARTIK M.;RIVERA JOCELYN;CHAN TIN-YAU;MADISON VINCENT S.;FISCHMANN THIERRY O.;DILLARD LAWRENCE W.;TRAN VINH D.;HE ZHENMIN;JAMES RAY ANTHONY;PARK HAENGSOON;PARADKAR VIDYADHAR M.;HOBBS DOUGLAS WALSH;KIRSCHMEIER PAUL;BANNERJI RAJAT |
| 分类号 |
C07D487/04;A61K31/519;A61P35/00 |
主分类号 |
C07D487/04 |
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