| 发明名称 |
Cyclophosphamide in combination with anti-idiotypic vaccines |
| 摘要 |
The present invention relates to methods of treating a cancer and in particular, a B-cell derived cancer, using a lymphocytotoxic but hematopoeitic cell sparing high-dose pulsed amount of an oxazaphosphorine drug in combination with immune therapeutics such as, for example, an autologous idiotypic vaccine and monoclonal antibodies that selectively bind B-cell specific antigens. |
| 申请公布号 |
US8673321(B2) |
申请公布日期 |
2014.03.18 |
| 申请号 |
US201113230212 |
申请日期 |
2011.09.12 |
| 申请人 |
BRODSKY ROBERT A.;JONES RICHARD J.;O'DONNELL, JR. FRANCIS E.;BONITZ SUSAN;SANTOS CARLOS;THE JOHNS HOPKINS UNIVERSITY;ACCENTIA BIOPHARMACEUTICALS, INC. |
发明人 |
BRODSKY ROBERT A.;JONES RICHARD J.;O'DONNELL, JR. FRANCIS E.;BONITZ SUSAN;SANTOS CARLOS |
| 分类号 |
A61K45/00;A61K31/675;A61K39/395 |
主分类号 |
A61K45/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
