发明名称 |
RNAi-mediated inhibition of phosphodiesterase type 4 for treatment of cAMP-related ocular disorders |
摘要 |
RNA interference is provided for inhibition of phosphodiesterase type 4 mRNA expression for treating patients with a cAMP-related ocular disorder. Phosphodiesterase type 4 mRNA targets include mRNA for 4A, 4B, 4C, and 4D phosphodiesterase isoforms. |
申请公布号 |
US8673873(B1) |
申请公布日期 |
2014.03.18 |
申请号 |
US20090580663 |
申请日期 |
2009.10.16 |
申请人 |
YANNI JOHN M.;CHATTERTON JON E.;GAMACHE DANIEL A.;MILLER STEVEN T.;ALCON RESEARCH, LTD. |
发明人 |
YANNI JOHN M.;CHATTERTON JON E.;GAMACHE DANIEL A.;MILLER STEVEN T. |
分类号 |
C12N15/11;C07H21/02;C12N15/00 |
主分类号 |
C12N15/11 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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