发明名称 |
Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
摘要 |
A method and device for local delivery of water-soluble or water-insoluble therapeutic agents to the surface of a normal or diseased body lumen is disclosed. An expandable structure of a medical disposable device, such as a balloon of a balloon catheter, is coated with an amphiphilic polymer coating comprising a therapeutic agent and an amphiphilic polymer or co-polymer. The medical disposable device is inserted into a body lumen, and expanded to contact the amphiphilic polymer coating against the body lumen. The total solubility of the polymer or co-polymer in vivo prevents any embolic hazard associated with the amphiphilic polymer coating. |
申请公布号 |
US8673332(B2) |
申请公布日期 |
2014.03.18 |
申请号 |
US201213560538 |
申请日期 |
2012.07.27 |
申请人 |
MICHAL EUGENE T.;LERNER DANIEL J.;POLLMAN MATTHEW J.;COVIDIEN LP |
发明人 |
MICHAL EUGENE T.;LERNER DANIEL J.;POLLMAN MATTHEW J. |
分类号 |
A61F13/00;A61F2/958;A61K9/00 |
主分类号 |
A61F13/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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