发明名称 |
Nucleotides and oligonucleotides for nucleic acid sequencing |
摘要 |
Embodiments of the invention provide non-natural bifunctional nucleotides having both nuclease resistance and nucleic acid synthesis blocking properties and methods of sequencing nucleic acids that employ non-natural bifunctional nucleic acids. Additional embodiments provide non-natural oligonucleotides and methods for sequencing nucleic acids using the non-natural oligonucleotides. Methods according to embodiments of the invention employ electronic detection and fluorescent detection of nucleic acid sequencing reactions. |
申请公布号 |
US8674086(B2) |
申请公布日期 |
2014.03.18 |
申请号 |
US20100823995 |
申请日期 |
2010.06.25 |
申请人 |
LIU JIANQUAN;SU XING;WU KAI;INTEL CORPORATION |
发明人 |
LIU JIANQUAN;SU XING;WU KAI |
分类号 |
C07H19/20;C07H19/00;C07H19/04 |
主分类号 |
C07H19/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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