| 发明名称 |
JAK2 inhibitors and their use for the treatment of myeloproliferative diseases and cancer |
| 摘要 |
The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds inhibit tyrosine kinase activity of JAK2, thereby making them useful as antiproliferative agents for the treatment of cancer and other diseases. |
| 申请公布号 |
US8673933(B2) |
申请公布日期 |
2014.03.18 |
| 申请号 |
US201213459742 |
申请日期 |
2012.04.30 |
| 申请人 |
PURANDARE ASHOK V.;GREBINSKI JAMES W.;HART AMY C.;INGHRIM JENNIFER;SCHROEDER GRETCHEN M.;WAN HONGHE;BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
PURANDARE ASHOK V.;GREBINSKI JAMES W.;HART AMY C.;INGHRIM JENNIFER;SCHROEDER GRETCHEN M.;WAN HONGHE |
| 分类号 |
A61K31/437;C07D487/14 |
主分类号 |
A61K31/437 |
| 代理机构 |
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