The invention provides immunosuppressive polypeptides and nucleic acids encoding such polypeptides. In one aspect, the invention provides mutant CTLA-4 polypeptides and nucleic acids encoding mutant CTLA-4 polypeptides. Compositions and methods for utilizing such polypeptides and nucleic acids are also provided.
申请公布号
CA2703263(C)
申请公布日期
2014.03.18
申请号
CA20082703263
申请日期
2008.10.15
申请人
PERSEID THERAPEUTICS LLC
发明人
KARRER, ERIK E.;PAIDHUNGAT, MADAN M.;BASS, STEVEN H.;NEIGHBORS, MARGARET;PUNNONEN, JUHA;CHAPIN, STEVEN J.;VISWANATHAN, SRIDHAR;LARSEN, BRENT R.
