发明名称 |
Epoxide inhibitors of cysteine proteases |
摘要 |
Provided herein are novel epoxide inhibitors of cysteine proteases, compositions comprising the epoxide inhibitors, and packaged pharmaceuticals. Also provided are methods of inhibiting a papain-family cysteine protease and methods of treating or preventing a disease by administering a composition containing an epoxide inhibitor of the invention. The compositions may be administered in combination with another therapeutic agent. |
申请公布号 |
US8673904(B2) |
申请公布日期 |
2014.03.18 |
申请号 |
US20070762735 |
申请日期 |
2007.06.13 |
申请人 |
BOGYO MATTHEW S.;SADAGHIANI AMIR M.;VERHELST STEVEN;THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
BOGYO MATTHEW S.;SADAGHIANI AMIR M.;VERHELST STEVEN |
分类号 |
C07D303/48;A61K31/336;A61K31/40;A61K31/403;A61K31/4427;A61K31/4523;A61K31/496;A61K31/5377;A61P1/00;A61P11/00;A61P19/02;A61P21/00;A61P25/00;A61P29/00;A61P31/00;A61P35/00;A61P37/06;C07D207/00;C07D209/02;C07D213/02;C07D221/00;C07D295/00;C07D303/02;C07D401/12 |
主分类号 |
C07D303/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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