发明名称 P 2�4 receptor antagonist
摘要 A compound having the following formula (II) or a pharmacologically acceptable salt thereof is used as a P2X4 receptor antagonist: wherein each of R11 and R12 is hydrogen, C1-8 alkyl or the like; R13 is hydrogen, C1-8 alkyl or the like; R14 is hydrogen, C1-8 alkyl, C1-8 alkoxy, C1-8 alkyl having 1-3 halogens, C1-8 hydroxyalkyl, halogen, hydroxyl, nitro, cyano, amino, C1-8 alkylamino, benzenesulfonylamino optionally having a substituent, a heterocyclic group optionally having a substituent or the like; and the condensed ring consisting of W1 and the neighboring benzene ring is naphthalene, tetrahydronaphthalene, or indan ring.
申请公布号 US8673915(B2) 申请公布日期 2014.03.18
申请号 US201113811714 申请日期 2011.07.27
申请人 USHIODA MASATOSHI;SAKUMA SHOGO;TENDO ATSUSHI;IMAI TOSHIYASU;INOUE KAZUHIDE;NIPPON CHEMIPHAR CO., LTD. 发明人 USHIODA MASATOSHI;SAKUMA SHOGO;TENDO ATSUSHI;IMAI TOSHIYASU;INOUE KAZUHIDE
分类号 A61K31/498;C07D241/38 主分类号 A61K31/498
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