发明名称 DIAMINOPYRIMIDINES AS P2X3 AND P2X2/3 MODULATORS
摘要 Compounds of the formula (I) or pharmaceutically acceptable salts thereof, wherein A, D, E, G, J, X, Y, Z R6, R7 and R8 are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the compounds.
申请公布号 CA2619898(C) 申请公布日期 2014.03.18
申请号 CA20062619898 申请日期 2006.08.21
申请人 F. HOFFMANN-LA ROCHE AG 发明人 DILLON, MICHAEL PATRICK;JAHANGIR, ALAM;LUI, ALFRED SUI-TING;WILHELM, ROBERT STEPHEN
分类号 C07D239/48;A61K31/506;A61P11/00;A61P13/00;C07D401/12 主分类号 C07D239/48
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