发明名称 |
Microbial succinic acid producers and purification of succinic acid |
摘要 |
The present invention relates to bacterial strains, capable of utilizing glycerol as a carbon source for the fermentative production of succinic acid, wherein said strains are genetically modified so that they comprise a deregulation of their endogenous pyruvate-formate-lyase enzyme activity, as well as to methods of producing organic acids, in particular succinic acid, by making use of such microorganism. The present invention also relates to the downstream processing of the produced organic acids by cation exchange chromatography. |
申请公布号 |
US8673598(B2) |
申请公布日期 |
2014.03.18 |
申请号 |
US201013201547 |
申请日期 |
2010.02.12 |
申请人 |
SCHRODER HARTWIG;HAEFNER STEFAN;ABENDROTH GREGORY VON;HOLLMANN RAJAN;RADDATZ ALINE;ERNST HANSGEORG;GURSKI HANS;BASF SE |
发明人 |
SCHRODER HARTWIG;HAEFNER STEFAN;ABENDROTH GREGORY VON;HOLLMANN RAJAN;RADDATZ ALINE;ERNST HANSGEORG;GURSKI HANS |
分类号 |
C12N1/32;C12P1/04;C12P7/40;C12P7/46;C12P17/10 |
主分类号 |
C12N1/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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