| 发明名称 |
NEW HISTONE DEACETYLASE INHIBITORS BASED SIMULTANEOUSLY ON TRISUBSTITUTED 1H-PYRROLES AND AROMATIC AND HETEROAROMATIC SPACERS |
| 摘要 |
The present invention refers to compounds derived from trisubstituted 1H-pyrrole rings and aromatic rings, which have the following formula (I):
as well as to the procedure for their preparation and the use thereof for the treatment of cancer by inhibiting histone deacetylases and the therapeutic use of biological processes related to the mentioned inhibition. |
| 申请公布号 |
PT2483242(E) |
申请公布日期 |
2014.03.17 |
| 申请号 |
PT20100763676T |
申请日期 |
2010.10.01 |
| 申请人 |
UNIVERSIDAD DEL PAIS VASCO-EUSKAL HERRIKO UNIBERTSITATEA;IKERCHEM, S.L. |
发明人 |
FERNANDO PEDRO COSSÍO MORA;AIZPEA ZUBIA OLASCOAGA;YOSU ION VARA SALAZAR;EIDER SAN SEBASTIÁN LARZABAL;DORLETA OTAEGUI ANSA;MARÍA DEL CARMEN MASDEU MARGALEF;ENEKO ALDABA ARÉVALO |
| 分类号 |
C07D207/34;A61K31/40;A61K31/4025;A61P31/10;C07D401/12;C07D403/12;C07D405/04;C07D405/12;C07D409/04 |
主分类号 |
C07D207/34 |
| 代理机构 |
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代理人 |
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