发明名称 INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE
摘要 A compound selected from the group consisting of 1-(2-fluoro-5-((4-oxo-3,4,5,6,7,8-hexahydrophthalazin-1-yl)methyl)phenyl)pyrrolidine-2,5-dione and 4-(3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl)-5,6,7,8-tetrahydrophthalazin-1(2H)-one, or a pharmaceutically acceptable salt thereof, for use in treating leukemia, colon cancer, glioblastomas, lymphomas, melanomas, carcinomas of the breast or cervical carcinomas in a mammal by administering thereto a therapeutically acceptable amount of said compound.
申请公布号 HRP20140115(T1) 申请公布日期 2014.03.14
申请号 HR2014P000115T 申请日期 2014.02.06
申请人 ABBVIE INC. 发明人 GANDHI, VIRAJ B.;GIRANDA, VINCENT L.;GONG, JIANCHUN;PENNING, THOMAS D.;ZHU, GUI-DONG
分类号 A01N43/58;A61K31/495;A61K31/50;C07D237/32;C07D403/10;C07D403/12;C07D403/14 主分类号 A01N43/58
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