| 发明名称 |
ANTIBODY DRUG CONJUGATES (ADC) THAT BIND TO 158P1D7 PROTEINS |
| 摘要 |
Antibody drug conjugates (ADC's) that bind to 158P1D7 protein and variants thereof are described herein. 158P1D7 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in glioblastoma, lung cancer, bladder cancer, and breast cancer. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer. |
| 申请公布号 |
US2014072586(A1) |
申请公布日期 |
2014.03.13 |
| 申请号 |
US201313975214 |
申请日期 |
2013.08.23 |
| 申请人 |
SEATTLE GENETICS, INC.;AGENSYS, INC. |
发明人 |
MORRISON ROBERT KENDALL;AN ZILI;MORRISON KAREN JANE MEYRICK;SNYDER JOSH;JIA XIAO-CHI |
| 分类号 |
C07K16/18;A61K45/06;A61K47/48 |
主分类号 |
C07K16/18 |
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