发明名称 DAPHNE GENKWA EXTRACTS, AND PHARMACEUTICAL COMPOSITION CONTAINING FRACTIONS OF THE EXTRACTS OR COMPOUNDS SEPARATED FROM THE EXTRACTS AS ACTIVE INGREDIENTS FOR PREVENTING OR TREATING ATOPIC DERMATITIS
摘要 The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of Daphne genkwa, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.
申请公布号 US2014072664(A1) 申请公布日期 2014.03.13
申请号 US201214117737 申请日期 2012.05.17
申请人 KIM JAE WHA;AHN KYUNG SEOP;KANG HO BUM;OH SEI RYANG;GO JAE JONG;KIM JOO HEON;SUN JANG MI;SONG JAE SUNG;OH HYUN WOO;JI DA JUNG;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY 发明人 KIM JAE WHA;AHN KYUNG SEOP;KANG HO BUM;OH SEI RYANG;GO JAE JONG;KIM JOO HEON;SUN JANG MI;SONG JAE SUNG;OH HYUN WOO;JI DA JUNG
分类号 C07D493/08;A61K36/83 主分类号 C07D493/08
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