| 发明名称 |
NOVEL N-(4-(AZETIDINE-1-CARBONYL) PHENYL) - (HETERO-) ARYLSULFONAMIDE DERIVATIVES AS PYRUVATE KINASE M2 (PMK2) MODULATORS |
| 摘要 |
Compounds of general Formula (I), and compositions comprising compounds of general formula I that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer. |
| 申请公布号 |
US2014073625(A1) |
申请公布日期 |
2014.03.13 |
| 申请号 |
US201113994398 |
申请日期 |
2011.12.16 |
| 申请人 |
SALITURO FRANCESCO G.;SAUNDERS JEFFREY O.;YAN SHUNQI;AGIOS PHARMACEUTICALS, INC |
发明人 |
SALITURO FRANCESCO G.;SAUNDERS JEFFREY O.;YAN SHUNQI |
| 分类号 |
C07D401/12;C07D401/14 |
主分类号 |
C07D401/12 |
| 代理机构 |
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