| 发明名称 |
Diagnostic markers for ankylosing spondylitis and uses thereof |
| 摘要 |
Disclosed are methods and agents for detecting the presence or diagnosing the risk of ankylosing spondylitis (AS) in mammals. These methods are based on the detection of polymorphisms within any one or more of the ARTS-1 gene, the IL-23R gene, the TNFR1 gene locus, the TRADD gene locus and the chromosome loci 2P15 and 21Q22. The present invention also features methods for the treatment or prevention of AS based on the diagnosis. |
| 申请公布号 |
AU2008255641(B2) |
申请公布日期 |
2014.03.13 |
| 申请号 |
AU20080255641 |
申请日期 |
2008.05.29 |
| 申请人 |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD;THE UNIVERSITY OF QUEENSLAND;BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
BROWN, MATTHEW ARTHUR;REVEILLE, JOHN DUFFIN;WORDSWORTH, BRYAN PAUL |
| 分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
| 代理机构 |
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代理人 |
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