发明名称 THIENOPYRAZOLE DERIVATIVE HAVING PDE7 INHIBITORY ACTIVITY
摘要 To provide thienopyrazole derivatives inhibiting PDE 7 selectively, and therefore, enhance cellular cAMP level. Consequently, the compound is useful for treating various kinds of disease such as allergic diseases, inflammatory diseases or immunologic diseases. The compound is thienopyrazole compound represented by the following formula (I): [wherein, especially, R1 is a cyclohexyl, a cycloheptyl group or a tetrahydropyranyl group; R2 is methyl; R3 is a hydrogen atom; and R4 is a group: -CONR5R6 (in which any one of R5 and R6 is a hydrogen atom)].
申请公布号 US2014073799(A1) 申请公布日期 2014.03.13
申请号 US201314013168 申请日期 2013.08.29
申请人 DAIICHI SANKYO COMPANY, LIMITED 发明人 INOUE HIDEKAZU;MURAFUJI HIDENOBU;HAYASHI YASUHIRO
分类号 C07D231/18 主分类号 C07D231/18
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