Mechanically competent scaffold for ligament and tendon regeneration

摘要

A multi-region device for repair, regeneration or reconstruction in articular tissue injury such as torn ligaments and tendons is provided. The device comprises at least one degradable material and biocompatible non-degradable polymeric fiber-based material, in a three-dimensional braided scaffold. The two end sections (14a, b) are designed for attachment of the device at the site of implantation and are designed to allow bone cell ingrowth, and one or more middle regions (12) are designed to allow ligament or tendon cell ingrowth. 14 b t2 14a