发明名称 |
METHODS TO INHIBIT INTRACELLULAR GROWTH OF BACTERIA AND TO TREAT BACTERIA-MEDIATED DISEASES |
摘要 |
Disclosed is a method of preventing, treating or inhibiting bacterial infections. The method comprises administering at least one of the compounds disclosed herein. Also disclosed are methods of increasing acidity of bacterial phagosomes to inhibit bacterial growth, methods of increasing mitochondrial reactive oxygen species (mROS) generation to inhibit bacterial growth in a cell, pharmaceutical compositions and uses thereof. |
申请公布号 |
WO2014039011(A1) |
申请公布日期 |
2014.03.13 |
申请号 |
WO2013SG00388 |
申请日期 |
2013.09.04 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
SINGHAL, AMIT;DE LIBERO, GENNARO |
分类号 |
A61K31/7076;A61K31/04;A61K31/05;A61K31/155;A61K31/277;A61K31/343;A61K31/395;A61K31/41;A61K31/42;A61K31/4422;A61K31/451 |
主分类号 |
A61K31/7076 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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