CO-TRANSCRIPTIONAL ASSEMBLY OF MODIFIED RNA NANOPARTICLES
摘要
A method is provided for generating RNA nanoparticles having modified nucleotides and/or having increased nuclease resistance where the RNA nanoparticles are formed cotranscriptionally by T7 RNA polymerase in the presence of manganese ions.
申请公布号
WO2014039809(A2)
申请公布日期
2014.03.13
申请号
WO2013US58492
申请日期
2013.09.06
申请人
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES
