发明名称 SUBSTITUTED AMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS
摘要 In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, Z, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
申请公布号 KR20140031859(A) 申请公布日期 2014.03.13
申请号 KR20137023969 申请日期 2012.02.16
申请人 THERAVANCE, INC. 发明人 FLEURY MELISSA;GENDRON ROLAND;HUGHES ADAM D.
分类号 C07D249/04;A61K31/4192;A61P9/00;C07D249/18;C07D261/12 主分类号 C07D249/04
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