发明名称 |
Antibiotic Compositions for the Treatment of Gram Negative Infections |
摘要 |
Provided herein are novel compounds and novel protected compounds that can be derived from polymyxin, including, e.g., polymyxin A. The novel compounds have antibacterial properties against a diverse range of Gram negative bacteria and reduced toxicity compared to polymyxins such as polymyxin A. Also provided are antibacterial pharmaceutical compositions containing the novel compounds and novel protected compounds, as well as methods for preparing the antibacterial compounds and protected compounds. |
申请公布号 |
US2014073559(A1) |
申请公布日期 |
2014.03.13 |
申请号 |
US201313835470 |
申请日期 |
2013.03.15 |
申请人 |
BIOSOURCE PHARM, INC.;CUBIST PHARMACEUTICALS, INC.;CUBIST PHARMACEUTICALS, INC.;BIOSOURCE PHARM, INC. |
发明人 |
CURRAN WILLIAM V.;LIU CHRISTOPHER M.;BOMBARDIER AMY C.D.;LEESE RICHARD A.;HWANG YOU SEOK;LIPPA BLAISE S.;ZHANG YANZHI |
分类号 |
C07K7/62;A01N43/713 |
主分类号 |
C07K7/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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