MODULATION OF ENHANCER RNA MEDIATED GENE EXPRESSION
摘要
Disclosed herein are methods and compounds for inhibiting gene expression by inhibiting enhancer RNAs (eRNAs). Such methods and compounds are useful for reducing expression of certain genes, many of which are associated with a variety of diseases and disorders.
申请公布号
WO2013177248(A3)
申请公布日期
2014.03.13
申请号
WO2013US42163
申请日期
2013.05.22
申请人
ISIS PHARMACEUTICALS, INC.;GLASS, CHRISTOPHER, K.;ROSENFELD, MICHAEL, G.;LI, WENBO;LAM, MICHAEL, T.
发明人
GLASS, CHRISTOPHER, K.;ROSENFELD, MICHAEL, G.;LI, WENBO;LAM, MICHAEL, T.;FREIER, SUSAN, M.