发明名称 |
ISOINDOLINONE DERIVATIVES |
摘要 |
The present invention relates to compounds of the formula I, as well as pharmaceutically-acceptable salts thereof, pharmaceutical compositions containing said compounds and methods of using said compounds in the treatment or prophylaxis of diseases and disorders. The compounds and compositions disclosed herein are glucokinase activators useful for the treatment or prophylaxis of metabolic diseases and disorders, for example diabetes mellitus, including type II diabetes mellitus. |
申请公布号 |
EP2705033(A1) |
申请公布日期 |
2014.03.12 |
申请号 |
EP20120717736 |
申请日期 |
2012.04.30 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BERTHEL, STEVEN JOSEPH;KESTER, ROBERT FRANCIS;ORZECHOWSKI, LUCJA |
分类号 |
C07D403/12;A61K31/4155;A61K31/497;A61P3/10 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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