| 摘要 |
PURPOSE: An anticholesterol composition is provided to suppress the activities of HMG-CoA reductase and acyl-CoA:cholesterol acyltransferase (ACAT) and to lower cholesterol in serum using a Lycii radicis cortex-derived tyramine derivative, thereby preventing hyperlipidemia. CONSTITUTION: A method for preparing an anticholesterol tyramine derivative comprises the steps of: extracting Lycii radicis cortex powder with an ethanol solution and filtering the extract; concentrating the extract by compression; and performing Sep-Pak C18 cartridges column chromatography. The derivative is trans-N-p-coumaroyltyramine (CT) or trans-N-feruloyltyramine (FT). A functional food composition for anticholesterol and antioxidative effects contains the tyramine derivative as an active ingredient. |
