发明名称 |
SYNTHETIC PEPTIDE CAPABLE OF INDUCING EXPRESSION OF TYPE-2 TNF RECEPTOR AND USE THEREOF |
摘要 |
<p>This invention provides a TNFR2 expression-inducing composition comprising as an active ingredient a peptide having TNFR2 expression-inducing activity, and a method for producing cells that express TNFR2 selectively by use of the composition. The cell production method provided by this invention comprises: culturing at least one species of cells capable of expressing TNF receptor 2, and supplying the cells with a synthetic peptide consisting of a nuclear localization signal sequence (NLS) or a nucleolar localization signal sequence (NoLS) to enhance TNFR2 expression in the cells.</p> |
申请公布号 |
EP2706113(A1) |
申请公布日期 |
2014.03.12 |
申请号 |
EP20120779331 |
申请日期 |
2012.04.17 |
申请人 |
TOAGOSEI CO., LTD. |
发明人 |
KOBAYASHI, NAHOKO;YOSHIDA, TETSUHIKO;NIWA, MIKIO |
分类号 |
C12N5/10;A61K38/00;A61P5/50;A61P9/00;A61P25/28;A61P43/00;C07K14/47 |
主分类号 |
C12N5/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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