发明名称 ANTICORPO, CÉLULA DE HIBRIDOMA, AGENTE DE DIAGNÓTICO, MEDICAMENTO, MÉTODOS PARA PREVENIR/TRATAR CÂNCER, PARA INDUZIR APOPTOSE CÉLULAS CANCEROSAS , PARA INIBIR CRESCIMENTO DE CÉLULAS CANCEROSAS E PARA DESTRUIR CÉLULAS CANCEROSAS, USO DE UM ANICORPO MONOCLONAL E AGENTE PARA PREVENIR OU TRATAR CÂNCER DE MAMA.
摘要 A human monoclonal antibody against a protein comprising the same or substantially the same amino acid sequence as the amino acid sequence represented by SEQ ID NO: 1 or SEQ ID NO: 3, its partial peptide, or a salt thereof, is useful as an agent for preventing/treating cancer, etc., an apoptosis inducer of cancer cells, a growth inhibitor of cancer cells, a cytotoxic agent against cancer cells through a host defense mechanism mediated by the Fc region of an antibody, and so on.
申请公布号 BRPI0717024(A2) 申请公布日期 2014.03.11
申请号 BR2007PI17024 申请日期 2007.10.04
申请人 TAKEDA PHARMACEUTICAL COMPANY LIMITED 发明人 SHUJI SATO;TSUTOMU OSHIMA;TOMOFUMI KUROKAM
分类号 C07K16/32;A61K39/395;A61P35/00;C07K16/18;C12N5/10;C12N15/02;C12P21/08 主分类号 C07K16/32
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