发明名称 Nuevos derivados dihidroquinolina-2-ona
摘要 <p>The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, A1, A2 and A3 are as described herein, compositions including the compounds and methods of using the compounds. These compounds are useful for therapy or prophylaxis in a mammal, and in particular as aldosterone synthase (CYP11B2 or CYP11B1) inhibitors for the treatment or prophylaxis of chronic kidney disease, congestive heart failure, hypertension, primary aldosteronism and Cushing syndrome.</p>
申请公布号 CO6890099(A2) 申请公布日期 2014.03.10
申请号 CO20140040934 申请日期 2014.02.26
申请人 F.HOFFMANN-LA ROCHE AG 发明人 AEBI JOHANNES;AMREIN KURT;HORNSPERGER BENOIT;KNUST HENNER;KUHN BERND;LIU YONGFU;MAERKI HANS PETER;MAYWEG ALEXANDER;MOHR PETER;TAN XUEFEI;ZHOU MINGWEI
分类号 C07D401/04 主分类号 C07D401/04
代理机构 代理人
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