PHARMACEUTICAL COMPOSITIONS FOR EXTENDED RELEASE OF AZO-BONDED 5-AMINOSALICYLIC ACID COMPOSITIONS

摘要

Gastric retentive dosage forms for sustained release of an azo-bonded prodrug of 5-aminosalicylic acid (5-ASA) are described which may allow once- or twice-daily dosing for both acute and long-term treatment of inflammatory bowel disorders. Methods of treatment using the dosage forms and methods of making the dosage forms are also described.