发明名称 Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
摘要 The present invention relates to compounds of Formula I and pharmaceutically acceptable salts, solvates, and hydrates thereof, that are useful as single pharmaceutical agents or in combination with one or more additional pharmaceutical agents, such as, a DPP-IV inhibitor, a biguanide, an alpha-glucosidase inhibitor, an insulin analogue, a sulfonylurea, an SGLT2 inhibitor, a meglitinide, a thiazolidinedione, or an anti-diabetic peptide analogue, in the treatment of for example, a disorder selected from: a GPR119-receptor-related disorder; a condition ameliorated by increasing a blood incretin level; a condition characterized by low bone mass; a neurological disorder; a metabolic-related disorder; type 2 diabetes; obesity; and complications related thereto.
申请公布号 US2014066369(A1) 申请公布日期 2014.03.06
申请号 US201214112384 申请日期 2012.04.18
申请人 JONES ROBERT M.;BUZARD DANIEL J.;HAN SANGDON;KIM SUN HEE;LEHMANN JUERG;YUE DAWEI;ZHU XIUWEN;ARENA PHARMACEUTICALS, INC. 发明人 JONES ROBERT M.;BUZARD DANIEL J.;HAN SANGDON;KIM SUN HEE;LEHMANN JUERG;YUE DAWEI;ZHU XIUWEN
分类号 C07D295/205;A61K31/495;A61K31/496;A61K31/499;A61K31/4995;A61K31/506;A61K45/06;C07D239/42;C07D241/38;C07D249/08;C07D257/04;C07D271/07;C07D403/12;C07D487/08 主分类号 C07D295/205
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