摘要 |
[Problem] As a possible alternative means to thermal modification, to provide a device for modifying a double-stranded nucleic acid to a single-stranded nucleic acid, and a method for modifying a double-stranded nucleic acid to a single-stranded nucleic acid. [Solution] This nucleic acid modification device (100) has a vibration generator (10) for generating vibration applied to a nucleic acid solution containing a double-stranded nucleic acid, and the double-stranded nucleic acid in the nucleic acid solution is modified to a single-stranded nucleic acid by applying the vibration generated in the vibration generator to the nucleic acid solution. |