发明名称 |
NOVEL ANTI-DR5 ANTIBODY |
摘要 |
The present invention relates to an antibody which has a therapeutic effect on cancer, an autoimmune disease, or an inflammatory disease. That is, the present invention relates to an antibody which exhibits a cytotoxic activity against death domain-containing receptor-expressing cells through apoptosis. [Object] An object of the invention is to provide a pharmaceutical having a therapeutic effect on cancer. [Means for Resolution] A novel anti-DR5 antibody capable of inducing apoptosis in cells has more potent cytotoxic activity than currently available anti-DR5 antibodies. |
申请公布号 |
KR20140027050(A) |
申请公布日期 |
2014.03.06 |
申请号 |
KR20137010556 |
申请日期 |
2011.10.27 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
OHTSUKA TOSHIAKI;TAKIZAWA TAKESHI;OGUNI AKIKO;MATSUOKA TATSUJI;YOSHIDA HIROKO;MATSUI YUMI |
分类号 |
C07K16/28;A61K39/395;A61P35/00;C12N15/13 |
主分类号 |
C07K16/28 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|