发明名称 1,2,4-TRIAZOLE DERIVATIVE INCLUDING SULFAMATE GROUP AS AROMATASE INHIBITOR
摘要 PROBLEM TO BE SOLVED: To provide a new compound appropriate for inhibiting the steroid sulfatase activity and the aromatase activity.SOLUTION: A compound represented by formula (I) is provided, where each T represents a bond with one of H, hydrocarbyl, -F-R- and D, E, P, or Q, or forms into a ring together with one of P and Q; Z is a proper atom having a valence of m; D, E, and F are proper linker groups independent from each other, and for Z of nitrogen, E is other than CHand C=O; P, Q, and R are ring systems independent from each other; and at least Q includes a sulfamate group.
申请公布号 JP2014040488(A) 申请公布日期 2014.03.06
申请号 JP20130249821 申请日期 2013.12.03
申请人 STERIX LTD 发明人 POTTER BARRY VICTOR LLOYD;WOO LOK WAI LAWRENCE;PUROHIT ATUL;READ MICHAEL J;BUBERT CHRISTIAN;SUTCLIFFE OLIVER BROOK
分类号 C07D249/08;C12Q1/02;A61K31/4196;A61K31/423;A61K31/424;A61K31/428;A61K45/00;A61P1/02;A61P1/04;A61P1/14;A61P1/16;A61P3/10;A61P5/14;A61P7/00;A61P9/00;A61P9/10;A61P11/02;A61P11/06;A61P13/00;A61P13/12;A61P15/00;A61P15/06;A61P15/18;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P21/04;A61P25/00;A61P25/06;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P27/06;A61P27/16;A61P29/00;A61P31/04;A61P31/18;A61P35/00;A61P35/02;A61P35/04;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D249/14;C07D413/12;C07D417/12;C07D521/00;C12Q1/34 主分类号 C07D249/08
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