发明名称 |
SYSTEMS AND METHODS FOR CONTROLLING TEMPERATURE OF SMALL VOLUMES |
摘要 |
Systems and methods for controlling the temperature of small volumes such as yoctoliter volumes, are described. The systems include one or more plasmonic nanostructures attached at or near a nanopore. Upon excitation of the plasmonic nanostructures, such as for example by exposure to laser light, the nanoparticles are rapidly heated thereby causing a change in the ionic conductance along the nanopore. The temperature change is determined from the ionic conductance. These temperature changes can be used to control rapid thermodynamic changes in molecular analytes as they interact with the nanopore. |
申请公布号 |
US2014064324(A1) |
申请公布日期 |
2014.03.06 |
申请号 |
US201314073126 |
申请日期 |
2013.11.06 |
申请人 |
NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY |
发明人 |
KASIANOWICZ JOHN J.;REINER JOSEPH E.;BALIJEPALLI ARVIND K.;ROBERTSON JOSEPH W.;BURDEN DANIEL L.;BURDEN LISA |
分类号 |
G01N25/00 |
主分类号 |
G01N25/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|