发明名称 PYRROLOPYRAZINE KINASE INHIBITORS
摘要 PROBLEM TO BE SOLVED: To provide compounds useful for treatment of autoimmune and inflammatory diseases.SOLUTION: Novel pyrrolopyrazine derivatives which inhibit Janus kinase (JAK) and spleen tyrosine kinase (SYK) are represented by the formula I, where R represents an alkyl, heteroaryl, carbonyl group or the like that may be substituted or a nitrogen or oxygen atom that may be substituted, and Qrepresents a phenyl group forming a heterocycle or heteroaryl ring together.
申请公布号 JP2014040460(A) 申请公布日期 2014.03.06
申请号 JP20130212832 申请日期 2013.10.10
申请人 F. HOFFMANN-LA ROCHE AG 发明人 DAISY JOE DUBOIS;ELWORTHY TODD RICHARD;ROBERT THAN HENDRICKS;JOHANNES CORNELIUS HERMANN;KONDRU RAMA K;LOU YAN;OWENS TIMOTHY D;PARK JAEHYEON;SMITH DAVID BERNARD;SOTH MICHAEL;YEE CALVIN WESLEY
分类号 C07D487/04;A61K31/4985;A61K31/538;A61P29/00;A61P37/02;A61P43/00 主分类号 C07D487/04
代理机构 代理人
主权项
地址