| 发明名称 |
SERINE/THREONINE KINASE INHIBITORS |
| 摘要 |
Compounds having the formula I wherein R2, X and Z as defined herein are inhibitors of ERK kinase. Also disclosed are compositions and methods for treating hyperproliferative disorders. |
| 申请公布号 |
US2014066453(A1) |
申请公布日期 |
2014.03.06 |
| 申请号 |
US201314011501 |
申请日期 |
2013.08.27 |
| 申请人 |
BLAKE JIM;CHEN HUIFEN;CHICARELLI MARK;GAUDINO JOHN;GAZZARD LEWIS;KINTZ SAM;MOHR PETE;ROBARGE KIRK;SCHWARZ JACOB;ZHOU AIHE;GENENTECH, INC.;ARRAY BIOPHARMA INC. |
发明人 |
BLAKE JIM;CHEN HUIFEN;CHICARELLI MARK;GAUDINO JOHN;GAZZARD LEWIS;KINTZ SAM;MOHR PETE;ROBARGE KIRK;SCHWARZ JACOB;ZHOU AIHE |
| 分类号 |
C07D471/04;C07D217/22;C07D401/12;C07D401/14;C07D405/12;C07D405/14 |
主分类号 |
C07D471/04 |
| 代理机构 |
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