SYSTEM AND METHOD FOR CLASSIFYING TISSUE OXYGENATION PROPERTIES BASED ON CLUSTER ANALYSIS OF THE MULTI-PARAMETRIC MR RESPONSE TO AN OXYGEN BREATHING CHALLENGE

摘要

A magnetic resonance (MR) imaging system (600) for generating information indicative of an MR response to an oxygen breathing challenge, the MRI (600) system comprising at least one controller (610) which is configured to define a reference region (302) within a region of interest (ROI) (300 A) of reconstructed MR image information (300) including a plurality of voxels, the reference region (302) comprising a plurality of reference voxels selected from the plurality of voxels, each of the plurality of voxels having associated DeltaR2* and DeltaR1 values; select a cluster of voxels comprising voxels from at least the reference voxels from a multiparametric DeltaR2* and DeltaR1 mapping of the plurality of voxels; determine AR2* and AR/ limit points based upon at least minimum DeltaR2* and DeltaR1 values of voxels of the cluster of voxels; and determine outlier voxels (115) based upon a comparison of DeltaR2* and DeltaR1 of at least one of the plurality of voxels with respective values of the DeltaR2* and DeltaR1 limit points.