Various embodiments provide byte caching in wireless communication networks. In one embodiment, a plurality of data packets are received through an internet protocol (IP) data flow established between a wireless communication device and at least one server. Each of the plurality of data packets are combined into a packet bundle. A determination is made as to whether a second byte caching system is available. The packet bundle is transformed using one or more byte caching operations based on a second byte caching system being available. The transformed packet bundle is sent to the second byte caching system using an IP communication mechanism.