发明名称 A METHOD TO IMPROVE PHARMACOKINETICS OF DRUGS
摘要 A compound comprises a pharmacologically active agent coupled to a plasma protein binding agent. The pharmacologically active agent, in some embodiments, may be an OLAM inhibitor. The plasma protein binding agent, in some embodiments, is a compound that is pharmacologically active in inflamed/injured tissue. A pharmaceutical composition that includes these compounds may be used to treat pain, shock, inflammatory conditions, or combinations thereof in a subject comprising administering to a subject who would benefit from such treatment a therapeutically effective amount of the pharmaceutical composition.
申请公布号 CA2922407(A1) 申请公布日期 2014.03.06
申请号 CA20132922407 申请日期 2013.08.30
申请人 BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 发明人 HARGREAVES, KENNETH M.
分类号 A61K38/46;A61K38/18;A61K39/395;A61P35/00 主分类号 A61K38/46
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