发明名称 |
COMBINATIONS OF SGLT 2 INHIBITORS AND ANTIHYPERTENSIVE DRUGS |
摘要 |
<p>Provided is a medicinal agent or a treatment method, in which a combination of an SGLT2 inhibitor and an anti-hypertension drug is used, and which is useful for the treatment of such diseases that at least hypertension or diabetes is included as a risk factor for a cardiovascular event. According to the present invention, an excellent hypotensive effect, which cannot be achieved when an anti-hypertension drug is used alone, can be achieved. Therefore, the conventional problem of using at least two types of anti-hypertension drugs for achieving a desired hypotensive effect can be solved. Furthermore, the present invention exerts a significant therapeutic effect on diabetes, a diabetes-related disease or a diabetes complication, particularly diabetic nephropathy. Furthermore, the present invention is also useful for the treatment of a disease in which the renal function is deteriorated.</p> |
申请公布号 |
CA2883118(A1) |
申请公布日期 |
2014.03.06 |
申请号 |
CA20132883118 |
申请日期 |
2013.08.30 |
申请人 |
TAISHO PHARMACEUTICAL CO., LTD. |
发明人 |
KOJIMA, NAOKI;ROMAN, J. RICHARD;MIYATA, NORIYUKI;TAKAHASHI, TEISUKE;TOMOIKE, HIDEKI;TAKEDA, TAKUYA |
分类号 |
A61K45/06;A61K31/382;A61K31/401;A61K31/41;A61P9/12;A61P31/10 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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