发明名称 |
Substituted (E)-N'-(1-phenylethylidene) benzohydrazide analogs as histone demethylase inhiitors |
摘要 |
In one aspect, the invention relates to substituted (E)-N'-(1- phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
申请公布号 |
AU2012296639(A1) |
申请公布日期 |
2014.03.06 |
申请号 |
AU20120296639 |
申请日期 |
2012.08.15 |
申请人 |
UNIVERSITY OF UTAH RESEARCH FOUNDATION |
发明人 |
VANKAYALAPATI, HARIPRASAD;SORNA, VENKATASWAMY;WARNER, STEVE L.;BEARSS, DAVID J.;SHARMA, SUNIL;STEPHENS, BRET |
分类号 |
A01N37/36;C07C241/00;C07C243/00 |
主分类号 |
A01N37/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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