发明名称 |
METHOD FOR PRODUCTION OF NON-NATURAL ANTIBIOTIC |
摘要 |
Disclosed is a transformant prepared by introducing a ketoreductase gene involved in the biosynthesis of L-epivancosamine into an actinobacterium originally capable of producing daunorubicin. Also disclosed is a process of efficiently producing a non-natural daunorubicin derivative using the transformant. The transformant is capable of efficiently producing a non-natural daunorubicin derivative such as epidaunorubicin. |
申请公布号 |
EP2192171(B1) |
申请公布日期 |
2014.03.05 |
申请号 |
EP20080830223 |
申请日期 |
2008.09.12 |
申请人 |
MEIJI SEIKA KAISHA LTD. |
发明人 |
SUMIDA, NAOMI;WATANABE, MANABU;YANAI, KOJI |
分类号 |
C12N1/21;C12N9/04;C12P17/06;C12P19/44;C12P19/56 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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