Chimeric and humanised monoclonal antibodies against interleukin-13

摘要

The present invention relates to immunoglobulins that specifically bind Interleukin 13 (IL-13), particularly human IL-13 (hIL-13). The present invention particularly concerns immunoglobulins which specifically bind the epitope set forth in SEQ ID. NO:84 of Seq I. D. NO:9 and moedulate the interaction between hIL-13 and hIL-13R. The present invention also concerns methods of treating diseases or disorders with said immunoglobulins, pharmaceutical compositions comprising said immunoglobulins and methods of manufacture.